Introduction: mental illnesses in the elderly population continue to increase worldwide, which is why research aimed at non-pharmacological intervention is very important, which will allow the stimulation of cognitive activity through interesting routines and activities. and nearby in older adults with cognitive impairment, thus allowing them to stop the progress of the deterioration and the comorbidities that cause this type of disease. Objective: to determine the effectiveness of a non-pharmacological neurointervention program in adults with cognitive impairment in a captive population from Sincelejo, Sucre-Colombia. Methodology: it was based on the selection of a control group and an experimental group, to which neurocognitive therapy was applied consecutively for a period of three months, three times a week, with a daily duration per patient of about 30 minutes. Results: improvement was found in terms of cognitive impairment in patients undergoing non-pharmacological therapy compared to the control group. Conclusion: it is recommended to apply this type of programs in elderly people.