Evaluation of Vascular Reactivity of Maternal Vascular Adaptations of Pregnancy With Quantitative MRI : Pilot Study
- Resource Type
- Authors
- Samuel Parry; Felix W. Wehrli; Alessandra Caporale; Nadav Schwartz; Michael C. Langham
- Source
- Journal of Magnetic Resonance Imaging. 53:447-455
- Subject
- medicine.medical_specialty
Population
Pilot Projects
Vasodilation
Pulse Wave Analysis
030218 nuclear medicine & medical imaging
Preeclampsia
03 medical and health sciences
Vascular Stiffness
0302 clinical medicine
Pregnancy
Internal medicine
Humans
Medicine
Radiology, Nuclear Medicine and imaging
Prospective Studies
Endothelial dysfunction
education
Reactive hyperemia
Pulse wave velocity
education.field_of_study
business.industry
medicine.disease
Magnetic Resonance Imaging
Arterial stiffness
Cardiology
Female
business
- Language
- ISSN
- 1522-2586
1053-1807
BACKGROUND Abnormal maternal vascular function during pregnancy stemming from systemic endothelial dysfunction (EDF) has a central role in the pathophysiology of preeclampsia (PE). PURPOSE To utilize quantitative MRI to investigate changes in physiological measures of vascular reactivity during normal pregnancy, and to explore EDF associated with preeclampsia. STUDY TYPE Prospective. POPULATION Healthy pregnant (HP) (n = 14, mean GA = 26 ± 7 weeks) and nonpregnant women (NP; n = 14); newly postpartum (PP