Noncovalent Interactions of Fluorine with Amide and CH
- Resource Type
- Authors
- Ning, Xi; Xiaohua, Sun; Minxiong, Li; Mingming, Sun; Michael A, Xi; Zeping, Zhan; Jia, Yao; Xu, Bai; Yanjun, Wu; Min, Liao
- Source
- The Journal of organic chemistry. 83(19)
- Subject
- Language
- ISSN
- 1520-6904
We designed and synthesized N-phenyl γ-lactam derivatives possessing two covalently identical ortho-F nuclei on the N-phenyl group. The F nuclei sited in different chemical environments where they were spatially adjacent to amide and alkyl groups due to hindered rotation around the central N-Ar bond.