Understanding the Mechanisms Driving Ectopic Bone Formation in a Zebrafish FOP Model
- Resource Type
- Authors
- Pamela C. Yelick; Melissa LaBonty
- Source
- The FASEB Journal. 29
- Subject
- animal structures
Cartilage
Anatomy
ACVR1
Biology
biology.organism_classification
Biochemistry
Ectopic bone formation
Cell biology
Family member
medicine.anatomical_structure
embryonic structures
Genetics
medicine
Bone formation
Receptor
Molecular Biology
Zebrafish
Biotechnology
- Language
- ISSN
- 1530-6860
0892-6638
Introduction: The zebrafish Type I TGFβ family member receptor, Alk8, modulates BMP/TGFβ signaling to promote cartilage and bone formation. Activating mutations in the human ortholog of Alk8, ACVR1...