Aims: To determine the cause of death of people with type 2 diabetes in Ayrshire and Arran between 2009 and 2014 compared to the national mortality rate. Methods: The primary cause of death (as noted on the death certificates) of 2116 patients with type 2 diabetes between the years 2009 and 2014 were collated. The causes of death were clustered into nine categories- heart disease, stroke, infection, renal failure, respiratory disorders, cancer, mental health, decompensated diabetes and other. The total rates were then compared to national rates using Standardised Mortality Ratio (SMR) and then individually due to heart disease, cerebrovascular disease and cancer. Results: The most common cause of death in the cohort was cancer (27.8%) followed by heart disease (24.1%). SMR for type 2 diabetes was 145 (95% CI 139,152; p15 years). SMR for strokes was elevated in the 55-74 age range with no significant gender difference. Cancer deaths in males was not significantly elevated (SMR 109) but it was elevated in females (120, 95% CI 104,137) (p Conclusions: The all-cause mortality for patients with type 2 diabetes was consistently higher across all age brackets. The greatest differences were noted in females with heart disease aged less than 65. Disclosure C. Meney: None. A. Collier: None. M.D. Hair: None. L. Cameron: None. C. Bisambar: None. J. Ilyas: None.