Palladium-catalysed O -Allylation of α-Hydroxyphosphonates: An Expedient Entry into Phosphono-oxaheterocycles
- Resource Type
- Authors
- Aurélie Dos Santos; Nicolas Fincias; Mansour Dolè Kerim; Martin Cattoen; Stellios Arseniyadis; Laurent El Kaim
- Source
- Advanced Synthesis and Catalysis
Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2018, 360 (3), pp.449-454. ⟨10.1002/adsc.201701150⟩
- Subject
- Metacyclophanes
010405 organic chemistry
[CHIM.ORGA]Chemical Sciences/Organic chemistry
chemistry.chemical_element
General Chemistry
Pudovik reaction
010402 general chemistry
Metathesis
01 natural sciences
0104 chemical sciences
Ring-closing metathesis
chemistry
Organic chemistry
α-Hydroxyphosphonates
O-allylation
Palladium
- Language
- English
- ISSN
- 1615-4150
1615-4169
International audience; We report here an unprecedented palladium‐catalysed O‐allylation of α‐hydroxyphosphonates. The method was eventually included in a sequential Pudovik/Tsuji‐Trost type O‐allylation/Ring‐Closing Metathesis to afford a variety of phosphorylated heterocycles of various sizes ranging from 5 to 16 starting from readily available aldehydes.