The predictive value of the CHA2DS2-VASc score in patients with mechanical mitral valve thrombosis
- Resource Type
- Authors
- Emre Aruğaslan; Muhammed Keskin; Ahmet Taha Alper; Mahmut Uluganyan; Veysel Ozan Tanık; Metin Çağdaş; Ahmet Öz; Mert İlker Hayıroğlu; Tufan Çınar
- Source
- Journal of Thrombosis and Thrombolysis. 45:571-577
- Subject
- medicine.medical_specialty
030204 cardiovascular system & hematology
Risk Assessment
03 medical and health sciences
0302 clinical medicine
Mechanical Mitral Valve
Internal medicine
Mitral valve
medicine
Humans
030212 general & internal medicine
Thrombus
Prosthetic Valve Thrombosis
Aged
Retrospective Studies
business.industry
Thrombosis
Atrial fibrillation
Retrospective cohort study
Hematology
Middle Aged
medicine.disease
medicine.anatomical_structure
Case-Control Studies
Heart Valve Prosthesis
Multivariate Analysis
CHA2DS2–VASc score
Cardiology
Mitral Valve
Cardiology and Cardiovascular Medicine
business
- Language
- ISSN
- 1573-742X
0929-5305
Prosthetic valve thrombosis (PVT) is a potentially life-threatening complication associated with high morbidity and mortality. The CHA2DS2-VASc is a clinical score used to determine thromboembolism risk in non-valvular atrial fibrillation patients. Therefore; in this study, we aimed to determine predictive value of the CHA2DS2-VASc score for development of PVT in patients with mechanical prosthetic valve. This was a retrospective study included 417 consecutive patients with mechanic prosthetic valve in whom transesophageal echocardiography (TEE) was performed due to different clinical indications from January 2004 to June 2016. After evaluation according to exclusion criteria, 267 patients with mechanic prosthetic valve were enrolled in the study. The definitive diagnosis of the PVT was made as proposed by TEE finding. The study population was divided into two groups; PVT patients (154 patients) and control group (113 patients) with functional prosthetic valve. The CHA2DS2-VASc score was calculated for each patient from the hospital electronic database. The mechanical mitral valve thrombosis predictive value of variables including CHA2DS2-VASc score was tested in our study. The mean CHA2DS2-VASc score was significantly higher in PVT patients compared to control patients (2.51 ± 1.54 vs. 1.13 ± 1.21, p