This paper describes a new, environmentally-friendly co-solvent/fluorocarbon vapor degreasing process that uses partially fluorinated compounds such as hydrofluoroethers (HFEs) or hydrofluorocarbons (HFCs) in conventional vapor degreasing equipment. The new process can permanently replace both 1,1,1-trichloroethane and CFC-113, as well as HCFC-141b or other chlorinated solvents, in a wide variety of cleaning applications vital to industry. Most existing vapor degreasers can run the new process effectively.