PhoSim: A software simulation package designed for macroscopic and microscopic studies in the time-resolved optical tomography
- Resource Type
- Authors
- Ch. Pafilis; M. Mikeli; M. Zioga; A. Eleftheriou; A.-N. Rapsomanikis; Efstathios Stiliaris
- Source
- 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD).
- Subject
- Physics
Photon
medicine.diagnostic_test
business.industry
Scattering
Light scattering
030218 nuclear medicine & medical imaging
03 medical and health sciences
Time of flight
0302 clinical medicine
Optics
030220 oncology & carcinogenesis
medicine
Ray tracing (graphics)
Tomography
Photonics
Optical tomography
business
- Language
PhoSim is an optical ray tracing Monte-Carlo simulator capable of reproducing the physical processes taking place in a tissue environment when illuminated by Near-Infrared radiation. From a macroscopic point of view this can be accomplished by the proper manipulation of the Henyey-Greenstein phase parameter g, which represents a simple and analytical solution for the fast generation of a random scattering angle photon distribution. Microscopically, the program can simulate certain biological structures by placing a proper density of sub-cellular organelles inside the volume of interest, proportional to the wavelength of the radiation used at the study (∼750-1000 nm). The new version of this software package is able to create different type of phantoms in multi-layer environments and it is also equipped with a detailed Fate and Time of Flight information of each traveling photon. PHOSIM is a simple and useful tool for Time-Resolved Optical Tomographic studies; its basic functions and capabilities with optical tomographic examples are presented in this work.