Brain Metastasis from Breast Cancer: Molecular Mechanisms
- Resource Type
- Authors
- Leonard Medeiros Da Silva
- Source
- Subject
- Gene expression profiling
medicine.anatomical_structure
Breast cancer
business.industry
medicine
Cancer research
Breast cancer cells
Blood–brain barrier
medicine.disease
business
Neuroscience
Brain metastasis
- Language
Our understanding of how breast cancer cells can colonize the brain microenvironment has improved over the past decade due to large clinical–epidemiological studies, experimental mouse models, and the use of high-resolution gene expression profiling technologies. Nevertheless, there are still major gaps that remain poorly understood. This chapter aims to highlight achievements and future directions in this exciting area of research and challenging oncology practice.