Use of hepatitis B virus DNA quantitation to predict hepatitis B e antigen reversion in cases of chronic hepatitis B
- Resource Type
- Authors
- Francis K.L. Chan; Henry Lik-Yuen Chan; Joseph J.Y. Sung; Alex Yui Hui; Lawrence Cheung-Tsui Hung; May-Ling Wong
- Source
- Journal of clinical microbiology. 41(10)
- Subject
- Microbiology (medical)
Adult
Male
Hepatitis B virus
Adolescent
viruses
Reversion
medicine.disease_cause
Virus
Hepatitis B, Chronic
Orthohepadnavirus
Predictive Value of Tests
Virology
medicine
Humans
Hepatitis B e Antigens
Seroconversion
Hepatitis B Antibodies
Child
Aged
biology
business.industry
Remission Induction
virus diseases
Middle Aged
Viral Load
biology.organism_classification
digestive system diseases
Hepadnaviridae
HBeAg
Immunology
DNA, Viral
Female
Viral disease
business
- Language
- ISSN
- 0095-1137
Seventy-three chronic hepatitis B patients who had either hepatitis B e antigen (HBeAg) seroconversion (group I) or HBeAg-negative disease (group II) were studied. HBV DNA levels at HBeAg seroconversion (group I) and at initial visits (group II) were significantly lower among patients who were persistently negative for HBeAg than among those who underwent HBeAg reversion.