NADPH oxidase(s):new source(s) of reactive oxygen species in the vascular system?
- Resource Type
- Authors
- Cristof Meischl; Hans W.M. Niessen; L Van Heerebeek; Dirk Roos; W. Stooker; Chris J.L.M. Meijer
- Source
- Van Heerebeek, L, Meischl, C, Stooker, W, Meijer, C J L M, Niessen, H W M & Roos, D 2002, ' NADPH oxidase(s) : new source(s) of reactive oxygen species in the vascular system? ', Journal of Clinical Pathology, vol. 55, no. 8, pp. 561-8 .
- Subject
- Phagocyte
Endothelium
Reviews
Biology
medicine.disease_cause
Muscle, Smooth, Vascular
Pathology and Forensic Medicine
medicine
Animals
Humans
NADH, NADPH Oxidoreductases
chemistry.chemical_classification
Reactive oxygen species
Oxidase test
NADPH oxidase
General Medicine
medicine.anatomical_structure
Enzyme
chemistry
Biochemistry
biology.protein
Blood Vessels
Signal transduction
Reactive Oxygen Species
Oxidative stress
Signal Transduction
- Language
- English
Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.