Purpose To assess optical quality before and after treatment with Meibopatch© (eyelid-warming device) in patient with mild and severe Meibomian gland dysfunction. Methods The Meibopatch© was applied for 5 minutes twice a day for one month to 20 eyes of 10 patients who exhibited dry-eye symptoms (OSDI), decreased tear film break-up time (TFBUT) due to altered meibomian gland secretions. We examined TFBUT, meibomian gland secretions, dry-eye symptoms, and assessed optical quality with OQAS (MTF and OSI) and Hartmann-Schack (RMS) aberrometry before, 15 days and 1 month after treatment. Results We have observed a significant improvement of the BUT, OSDI, Meibomian gland secretion quality, MTF and OSI after treatment. Conclusion The Meibopatch © eyelids warming device improved dry-eye symptoms, TFBUT and meibomian gland secretion quality. Our study showed also a significant improvement of both MTF and OSI.