Hepatic Artery Thrombosis After Adult Living Donor Liver Transplantation: The Effect of Center Volume
- Resource Type
- Authors
- Kian A. Modanlou; Michael Abecassis; Paolo R. Salvalaggio; Ann M. Harper; Erick B. Edwards
- Source
- Transplantation. 84:926-928
- Subject
- medicine.medical_specialty
Time Factors
Tissue and Organ Procurement
Databases, Factual
medicine.medical_treatment
Liver transplantation
Hepatic Artery
parasitic diseases
Living Donors
medicine
Humans
Retrospective Studies
Transplantation
Deceased donor
business.industry
Vascular disease
Graft Survival
Thrombosis
Patient survival
medicine.disease
Liver Transplantation
Surgery
Center volume
Hepatic artery thrombosis
Organ procurement
Treatment Outcome
Tissue and Organ Harvesting
Living donor liver transplantation
business
- Language
- ISSN
- 0041-1337
Background. To investigate whether center volume impacts the rate hepatic artery thrombosis (HAT) and patient survival after adult living donor liver transplantation (ALDLT). Methods. Patients with HAT who were listed as Status 1 in the Organ Procurement Transplant Network database were included in the study. Recipients of ALDLT were compared to those who received a deceased donor liver transplant (DDLT). Results. Recipients of ALDLT had a higher rate of HAT than recipients of DDLT. Centers that performed less than four adult ALDLT had a higher rate of HAT than other higher volume centers. “Novice” centers had a worse graft and patient survival than those with more experience in ALDLT. Recipients who had HAT experienced a worse patient survival than those who did not. Conclusions. Centers with higher volume have a lower rate of HAT and a better patient and graft survival in ALDLT. Clearer regulations and focus on overcoming the learning curve might be needed to increase the utilization of ALDLT.