Primary diffuse large B-cell lymphoma of the mandible
- Resource Type
- Authors
- José Vassallo; Graziella Chagas Jaguar; Juliana Mota Siqueira; Patrícia Maria Fernandes; Andrea Cruz Ferraz de Oliveira; Fábio de Abreu Alves
- Source
- Autopsy and Case Reports, Vol 9, Iss 3 (2019)
Autopsy & Case Reports
- Subject
- medicine.medical_specialty
Periodontal treatment
lcsh:Internal medicine
medicine.medical_treatment
Radiography
Oral Medicine
lcsh:Medicine
Head and Neck Neoplasms
Lymphoma
Pathology and Forensic Medicine
03 medical and health sciences
0302 clinical medicine
hemic and lymphatic diseases
Internal Medicine
medicine
Large B-Cell
lcsh:RC31-1245
Chemotherapy
business.industry
lcsh:R
Complete remission
Mandible
030206 dentistry
medicine.disease
Diffuse
Article / Clinical Case Report
030220 oncology & carcinogenesis
Radiology
Lymphoma, Large B-Cell, Diffuse
Differential diagnosis
business
Diffuse large B-cell lymphoma
- Language
- English
- ISSN
- 2236-1960
Primary intraosseous non-Hodgkin lymphoma in the mandible is uncommon, representing about 0.6% of all extranodal lymphomas. We present the case of a 51-year-old male with a 4-month complaint of mandibular swelling and paresthesia, which had been previously submitted to an unsuccessful periodontal treatment. The intra-oral evaluation showed an extensive swelling with teeth mobility in the right mandible body. The panoramic radiography and computed tomography images showed an extensive osteolytic lesion. An incisional biopsy was performed and the histopathological and immunohistochemical analysis established the diagnosis of diffuse large B-cell lymphoma. The treatment included six cycles of chemotherapy with complete remission. The patient is under the seventh month of follow-up with no evidence of relapse. Although uncommon in the oral cavity, lymphoma should be considered in the differential diagnosis.