Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy
- Resource Type
- Authors
- Michael Schär; Sabra C. Lewsey; Joevin Sourdon; Robert G. Weiss
- Source
- Heart Failure Clinics
Heart Failure Clinics, WB Saunders, 2021, 17 (1), pp.149-156. ⟨10.1016/j.hfc.2020.08.011⟩
Heart Failure Clinics, 2021, 17 (1), pp.149-156. ⟨10.1016/j.hfc.2020.08.011⟩
- Subject
- cardiomyopathies
spectroscopy
medicine.medical_specialty
Magnetic Resonance Spectroscopy
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging
Ischemia
Energy metabolism
030204 cardiovascular system & hematology
cardiac magnetic resonance
Patient care
03 medical and health sciences
0302 clinical medicine
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Internal medicine
medicine
Humans
030212 general & internal medicine
ComputingMilieux_MISCELLANEOUS
energetics
Myocardial energetics
Heart Failure
business.industry
Myocardium
General Medicine
medicine.disease
3. Good health
Metabolism
Heart failure
Cardiology
Cardiology and Cardiovascular Medicine
Cardiac magnetic resonance
business
Energy Metabolism
- Language
- ISSN
- 1551-7136
The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.