Increased superoxide in GCH1 mutant fibroblasts points to a dopamine-independent toxicity mechanism
- Resource Type
- Authors
- Peter Vangheluwe; Joanne Terbeek; David Nicholl; Wim Vandenberghe; Shaun Martin; Dorien Imberechts; Inge Kinnart
- Source
- Parkinsonism & Related Disorders. 82:10-12
- Subject
- Parkinson's disease
Dopamine
Dopamine Agents
Mutant
Pharmacology
chemistry.chemical_compound
Phenylketonurias
medicine
Humans
GTP Cyclohydrolase
Aged
Tetrahydrobiopterin
biology
Superoxide
Mechanism (biology)
Nitric oxide synthase
Parkinson Disease
GTP cyclohydrolase 1
Fibroblasts
Middle Aged
medicine.disease
Dopa-responsive dystonia
Dystonia
Neurology
chemistry
Toxicity
biology.protein
Neurology (clinical)
Nitric Oxide Synthase
Geriatrics and Gerontology
medicine.drug
- Language
- ISSN
- 1353-8020
ispartof: PARKINSONISM & RELATED DISORDERS vol:82 pages:10-12 ispartof: location:England status: published