BACKGROUND: Mindfulness-based interventions (MBIs) may offer a means for Latinx families to ameliorate stress, enhance emotion regulation, and foster social support. METHODS: We assessed pilot data from Latinx parents in Eastside Los Angeles (n = 27) matched with their children aged 10–16 (n = 32) to determine whether participation in a community-derived MBI was associated with greater improvements in dispositional mindfulness, perceived stress, emotion regulation, and family social support compared to a control condition. RESULTS: Compared to the control group, parents in the MBI group showed greater reductions in perceived stress scale (PSS) scores (B = −2.94, 95% CI [−5.58, −0.39], p = .029), while their children reported greater increases in perceived social support from family (B = 2.32 , 95% CI [0.26, 4.38], p = .027). DISCUSSION: Findings show a community-derived MBI may improve stress in Latinx parents and social support for their children.