Genome-wide alternation and effect of DNA methylation in the impairments of steroidogenesis and spermatogenesis after PM
- Resource Type
- Authors
- Zhonghao, Zhang; Jiankang, Wang; Fuquan, Shi; Yingqing, Li; Peng, Zou; Ying, Tang; Chang, Liu; Yimeng, Wang; Xi, Ling; Lei, Sun; Cuiqing, Liu; Yanshu, Zhang; Fei, Gao; Qing, Chen; Lin, Ao; Fei, Han; Jinyi, Liu; Jia, Cao
- Source
- Environment international. 169
- Subject
- Male
Semen
5-Methylcytosine
Humans
Particulate Matter
Testosterone
Cholesterol Side-Chain Cleavage Enzyme
DNA Methylation
Spermatogenesis
- Language
- ISSN
- 1873-6750
The effects of ambient fine particles on male reproductive health have raised widespread concern. The particular underlying mechanisms of the damage remain largely unclear and demand more research in new directions. Previous research has revealed that DNA methylation plays an important role in male reproductive development and is also vulnerable to environmental influences. However, there hasn't been enough investigation into the involvement of DNA methylation in PM