Osteoarthritis (OA) is the most common form of arthritis worldwide, and is reported to be the leading cause of disability in the United States [1, 2]. With the invention of an upright MRI (Fonar Corp., Melville, NY), it is now possible to image the knee of an upright, weight-bearing patient in truly functional positions to provide improved techniques for early evaluation of knee OA. However, scan set-up in a weight-bearing MRI is challenging because of limited space. To get a subject to a targeted knee flexion angle (KFA) and to have them maintain this angle for the duration of a scan is difficult.Copyright © 2009 by ASME