Risk Factors for Glaucoma in a Cohort of Patients with Fuchs Heterochromic Iridocyclitis
- Resource Type
- Authors
- Jaime Levy; Anthony J. Hall; Jennifer G Smith; Lyndell L Lim; Jason Toniolo
- Source
- Ocular immunology and inflammation. 25(6)
- Subject
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
Visual acuity
genetic structures
Adolescent
Visual Acuity
Ocular hypertension
Glaucoma
Iridocyclitis
Cataract
03 medical and health sciences
Young Adult
0302 clinical medicine
Risk Factors
Ophthalmology
Fuchs heterochromic iridocyclitis
Immunology and Allergy
Medicine
Humans
Aged
Retrospective Studies
business.industry
Incidence (epidemiology)
Incidence
Retrospective cohort study
Middle Aged
medicine.disease
eye diseases
030104 developmental biology
Cohort
030221 ophthalmology & optometry
Female
Ocular Hypertension
sense organs
medicine.symptom
business
Uveitis
Follow-Up Studies
- Language
- ISSN
- 1744-5078
To describe the incidence and risk factors for ocular hypertension and/or glaucoma in patients with Fuchs heterochromic iridocyclitis (FHC).Retrospective analysis of 88 patients with FHC. Kaplan-Meier curves estimated the time to develop cataract and ocular hypertension/glaucoma. Possible prognostic factors were investigated in univariate Kaplan-Meier analyses using the Mantel-Cox logrank test.At presentation with FHC, 52% of patients had a cataract and 26% of patients had ocular hypertension/glaucoma. The estimated percentage of patients with a cataract or ocular hypertension/glaucoma by 4 years after presentation was 71% (CI: 58-81%) and 39% (CI: 28-51%), respectively. Patients aged ≥50 years had significantly greater risk of developing glaucoma (p = 0.0065). After adjusting for age-group, having a cataract at presentation was associated with increased risk of glaucoma (p = 0.032).Risk factors for development of ocular hypertension/glaucoma were increasing patient age and having a cataract at presentation with FHC.