Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
- Resource Type
- Source
- Roberts, I, Shakur-Still, H, Afolabi, A, Akere, A, Arribas, M, Brenner, A, Chaudhri, R, Gilmore, I, Halligan, K, Hussain, I, Jairath, V, Javaid, K, Kayani, A, Lisman, T, Mansukhani, R, Mutti, M, Arif Nadeem, M, Pollok, R, Simmons, J, Soomro, M, Stanworth, S, Veitch, A, Hawkey, C, Cuzick, J, Henry, D, Metcalfe, C, Gray, R, Barkun, A, David, S, Devereaux, P, Brady, T, Coats, T, Edwards, P, Ker, K, Manno, D, Austin, E, Bal, K, Balogun, E, Barrow, C, Beaumont, D, Benyahia, M, Brooks, I, Cargill, M, Carrington, L, Frimley, L, Geer, A, Gilbert, D, Gilliam, C, Gil Onandia, J, Golfi, N, Hetherington, D, Howe, C, Hughes, C, I'anson, D, Jackson, R, Joshi, M, Kansagra, S, Kawahara, T, Kostrov, S, Miah, H, Ndungu, B, Needham, K, Outtandy, A, Pearson, D, Pepple, T, Prowse, D, Quashi, N, Quinn, A, Ramos, M, Ranopa, L, Reid, M, Roukas, C, Squires, C, Tanner, J, Thayne, A, Uddin, R, Fawole, B, Bello, F A, Olayemi, O, Okunade, O, Adetayo, O, Khamis, H, Shukri Bin Jahit, M, Gogichaishvili, T, Mateescu, R B, Adhikaree, A, Abdo, A E, Zaher, M, Deasy, C, Alvarez Gregori, J, Wellsh, B, Lawton, L, Kamath, R, Barry, A, Carpio, R, Finney, K, Maguire, H, James, M, Coffey, F, Gough, C, Sawers, L, Thi, A-A, Burnett, C, Jacques, N, Murray, V, Jarman, H, Lambe, C, Rounding, S, Tucker, S, Al-Idari, R, Guest, S, Stoddard, E, Yeo, D, Bergin, C, Hardy, E, Thunder, J, Jhalli, P, Hartley, E, Jarvis, C, Swann, C, Reed, M, Gallagher, B, Grahamslaw, J, O'Brien, R, Harris, T, Bellhouse, G, Boulton, O, Skene, I, Stanley, A, Johnstone, J, Maguire, D, Thornton, S, Banks, M, Bercades, G, Marks, D, Ryu, J, Dowty, C, Pott, J, East, J, Bailey, A, Beer, S, Davies, S, Appelboam, A, Mackle, D, Small, J, Vorwerk, C, Atkins, R, Bradbury, I, Bryceland, C, McClelland, L, Thomas, M, Clayton, K, Michael, A, Haig, S, Al-Nahhas, S, Godfrey, T, Boger, P, Comer, R, Watkins, B, Afolabi, O, Afzal, S, Cowton, A, Everett, S, Fazakerley, R, Onoviran, F, Snook, J, Berry, J, Simpson, D, Keep, J, Cotton, H, Helyar, S, Rutter, M, Johnston, T, O'Rourke, L, Chan, L, Tambellini, J, Trodd, D, Shutt, J, Moreton, S, Oglesby, A, Boyle, A, Haeger, N, Hardwick, S, Kendall, J, Faulkner, B, Worner, R, Hearnshaw, S, Doona, M, Price, M, Hunter, L, Bell, M, Loureiro, V, Kehoe, A, Jefferey, A, Squire, R, Hartin, D, Bell, S, Newman, A, Gagg, J, Foot, J, Wakeford, S, May, G, Bartram, T, Cumpstay, P, Parker, L, Das, R, Pahary, S, Wright, G, Butt, G, Christmas, N, Wilson, S, Ashfaq, M, Chandler, L, Demetriou, C, Kaye, P, Carley, S, Brown, A, Jones, L, Whileman, A, Greenaway, J, Tregonning, J, Kuhrt, A, Goodacre, S, Jones, J, Owen, C, Mitra, A, Harper-Payne, A, Trudgill, N, Hayes, A, Butt, F, Clifford, G, Kinnon, A, Fowler, S, Pillay, K, Gidwani, S, McNair, A, Omer, O, de Weymarn, T, Amin, A, Martin, J, Mathieu, N, Barnes, S, Turvill, J, Sweeting, H, Draegebo, M, McNaught, M, Grocutt, M, Margalef, J, Humphrey, J, Jackson, R, Bellis, F, Hunt, J, Stevenson, A, Watson, N, Barden, S, Paterson, S, Macdonald, C, Hobday, D, Orugun, O, Allison, A, Dyer, T, McBride, S, Sawicki, W, Rayner, B, Flowerdew, L, Barbour, J, Klein, J, Hood, S, Palmer, N, de Wolff, J, Shenoy, A, Swallow, P, Srirajaskanthan, R, Arshad, S, Aslam, N, Bangash, A, Qamar, M, Zahoor, H, Arshad, S, ain Ghalib, Q, Hameed, T, Saif, T, Shafi, W, Ali, A, Khan, S, Muaaz, M, Taj, A, Ghafoor, A, Afridi, A, Ahmad, M, Aslam, M, Kumar, S, Ali, M, Bughio, U, Chang, A, Shaikh, S, Ahmad, S, Ali, Z, Waqar, M, Mushir, A, Sattar, S, Goraya, S, Aslam, S, Fatima, N, Noreen, S, Saleem, S, Rahman, F, Iqbal, N, Khalid, M, Riaz, U, Umar, M, Akhter, T, Khan, J, Misbah, N, Afzal, M, Kayani, M, Shah, S, Tarar, S, Khan, S, Iqbal, Y, Khan, E, Reki, M, Hussain, T, Iqbal, S, Khurram, M, Shafi, M, Shaikh, A, Ahmed, A, Kumar, A, Sachdev, P, Nasir, K M, Chaudhry, Z I, Zubair, M, Tayyab, G, Mushtaq, J, Nasir, M, Khan, A, Ali, A, Ali, S, Uddin, W, Ahmed, S, Kazmi, T, Channa, S, Aman, A, Shaikh, M, Rizvi, T, Hussain, A, Baqai, H Z, Rasheed, Z, Khan, A, Irfan, A, Husain, A, Aslam, A, Yahya, K, Azhar, S, Ul Haq, M, Afzal, A, Imran, M, Saeed, I, Yusuf, A, Hassan, M, Marwat, M, Ishfaq, M, Bashir, T, Kumar, S, Yaqoob, S, Wahid, A, Fakoya, T, Oke, T, Tejan, E, Olaomi, O, Badejo, O, Nnaemaka, O, Ukwu, N, Arowolo, O, Aderounmu, A, Wuraola, F, Ugiagbe, R, Atiri, A, Eghaghe, E, Adekoya, A, Tade, A O, Shonoiki, O, Olatoke, S, Raji, T, Ekwunife, C, Onyekpere, C, Ahmed, A, Muhammad, D, Odeghe, E, Lesi, O, Osueni, A, Samaila, A, Nahuche, A, Ajayi, A, Dongo, A, Ijoma, U, Adebanjo, A T, Igetei, R, Yilkudi, M, Osisanya, K, Okeke, E N, Enwere, O O, Esmat, S, Ashoush, O, Naga, M, Nagy, F, Saiid, M, Shaker, A, Helmy, A, Saafan, S, Abdel Monem, M, Din, J, Azis, K, Brukan, M, Singh, S, Zakaria, A, Farid, S, Hashim, N, Mafauzy, M, Najmi, W, Amri, N, Yi, X, Hisyam, M, Ng, E, Ramli, Z, Yee Lim, S, Voon, K, Young Yam, S, Jahit, M, Joon, L, Melikidze, B, Kazaishvili, D, Grubelashvili, N, Mosidze, B, Tomadze, G, Megreladze, A, Oprita, R, Pestroiu Calescu, D, Chioncel, C, Ragea, A, Mateescu, B, Busuioc, B, Voiosu, A, Cotirlet, A, Pintilie, I, Jinga, M, Balaban, D, Tanău, M, Negreanu, L, Bataga, S, Priya, K, Baral, S, Anuj, K C A, Sah, V, Yadav, V, Abdo, A, Ahmed, D, Al Anazi, M, Al Balkhi, A, Álvarez Gregori, J, Fornieles Pérez, H & Beqiri, A 2020, ' Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial ', The Lancet . https://doi.org/10.1016/S0140-6736(20)30848-5
- Subject
Gastrointestinal bleeding Lower gastrointestinal bleeding business.industry Maintenance dose Placebo-controlled study General Medicine 030204 cardiovascular system & hematology A300 medicine.disease Placebo Loading dose 03 medical and health sciences 0302 clinical medicine Anesthesia Medicine 030212 general & internal medicine business Stroke Tranexamic acid medicine.drug - Language
- English
- ISSN
- 0140-6736