Design, Evolution, and Characterization of a Xylose Biosensor in Escherichia coli Using the XylR/xylO System with an Expanded Operating Range
- Resource Type
- Authors
- James M. Wagner; Rui-Qi Tang; Fengwu Bai; Xin-Qing Zhao; Hal S. Alper
- Source
- ACS Synthetic Biology. 9:2714-2722
- Subject
- technology, industry, and agriculture
Biomedical Engineering
macromolecular substances
General Medicine
Xylose
Directed evolution
medicine.disease_cause
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Combinatorial chemistry
Metabolic engineering
chemistry.chemical_compound
Synthetic biology
chemistry
medicine
Biosensor
Escherichia coli
Design evolution
- Language
- ISSN
- 2161-5063
Genetically encoded biosensors are extensively utilized in synthetic biology and metabolic engineering. However, reported xylose biosensors are far too sensitive with a limited operating range to b...