Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
- Resource Type
- Authors
- Svetlana Jankovic; Mirjana Sovilj; Tatjana Adamović; Ljiljana Jeličić; Miško Subotić; Aleksandar Gavrilovic; Ivana Bogavac
- Source
- International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3855, p 3855 (2020)
Volume 21
Issue 11
- Subject
- Adult
Auditory perception
Middle Cerebral Artery
medicine.medical_specialty
Hemodynamics
Gestational Age
Gravidity
Pulsatility index
Article
Catalysis
lcsh:Chemistry
Inorganic Chemistry
03 medical and health sciences
Fetus
0302 clinical medicine
Group differences
Pregnancy
Auditory stimulation
medicine.artery
Humans
Medicine
Physical and Theoretical Chemistry
Pulse
lcsh:QH301-705.5
Molecular Biology
Spectroscopy
030219 obstetrics & reproductive medicine
business.industry
Obstetrics
Organic Chemistry
General Medicine
medicine.disease
Computer Science Applications
parous and nulliparous pregnancy
lcsh:Biology (General)
lcsh:QD1-999
Acoustic Stimulation
fetal auditory perception
Middle cerebral artery
Auditory Perception
Female
business
030217 neurology & neurosurgery
- Language
- ISSN
- 1422-0067
Pulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant women divided into two groups. Group 1 consisted of 98 nulliparous women (C1 = 98) and Group 2 consisted of 98 parous women (C2 = 98). All pregnant women were of comparable age and fetal gestational age (GA) when MCA-PI values were recorded. Measurements of PI values in fetal MCA were obtained before and immediately after the application of fetal auditory stimulation test. The MCA-PI measuring was conducted in the period between the 36th and the 41st week of GA. The results showed that PI baseline values and PI values after defined auditory stimulation were significantly different when measured in nulliparous women compared to parous women (p = 0.001
p = 0.003, respectively), while no group differences were observed in relative PI value changes due to auditory stimulation. These findings suggest that hemodynamic changes in fetal MCA caused by defined auditory stimulation measured by PI value changes may be valuable in the assessment of fetal auditory perception functionality and its development.