This study describes the mental health of US adults with and without diabetes (ND) over an 18-month period of the COVID-pandemic. A 12-month web-based survey was administered in May 2020 (N = 2,176) to June 2021 and November 2021 (18MO; N = 1,192) including demographics, pandemic experiences, depression (PHQ-8) and anxiety (GAD-7) symptoms, perceived stress (PSS) , and resilience (BRS) . Mean age of 18MO Completers (55%) was 53 years (SD = 16.4) , primarily female (80%) , White (91%) , with an annual household income of ≥ $60,000 (58%) . 165 had type 2 diabetes (T2D; 14%) , 83 had prediabetes (7%) , and 56 had type 1 (T1D; 5%) . Completers were more likely to be White, educated (45% post-master’s degree) , and homeowners with fewer medical and emotional comorbidities at baseline than non-completers (all p Disclosure B.A.Myers: None. R.Klingensmith: None. I.Gonzalez casanova: None. M.De groot: None. Funding Indiana University Diabetes Translational Research Center