Figure S1. Accumulation of soluble, hyperphosphorylated tau in A152T-expressing mice. Figure S2. Increased tau phosphorylation in the sarkosyl-soluble S2 fraction in TauA152T-AAV mice. Figure S3. Neurodegeneration observed in TauA152T-AAV mice. Figure S4. Human tau expression is detected in the spinal cord of tau-AAV injected mice. Figure S5. Accumulation of soluble pT153 is specific to A152T carriers. (PDF 1530â kb)