Internal energy deposition and ion fragmentation in atmospheric-pressure mid-infrared laser ablation electrospray ionization
- Resource Type
- Authors
- Hehua Huang; Akos Vertes; Peter Nemes
- Source
- Physical Chemistry Chemical Physics. 14:2501
- Subject
- Ions
Spectrometry, Mass, Electrospray Ionization
Desorption electrospray ionization
animal structures
Matrix-assisted laser desorption electrospray ionization
Infrared Rays
Chemistry
Lasers
Electrospray ionization
Laser ablation electrospray ionization
Temperature
Extractive electrospray ionization
Analytical chemistry
General Physics and Astronomy
Ion source
Atmospheric-pressure laser ionization
Vitamin B 12
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Pressure
Physics::Atomic and Molecular Clusters
Physics::Atomic Physics
Physical and Theoretical Chemistry
Ambient ionization
- Language
- ISSN
- 1463-9084
1463-9076
Mid-infrared laser ablation of water-rich targets at the maximum of the 2.94 μm absorption band is a two-step process initiated by phase explosion followed by recoil pressure induced material ejection. Particulates and/or droplets ejected by this high temperature high pressure process can be ionized for mass spectrometry by charged droplets from an electrospray. In order to gauge the internal energy introduced in this laser ablation electrospray ionization (LAESI®) process, we apply the survival yield method and compare the results with electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI). The results indicate that LAESI yields ions with internal energies indistinguishable from those produced by ESI. This finding is consistent with the recoil pressure induced ejection of low micrometre droplets that does not significantly change the internal energy of solute molecules.