Hypocellular Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) Presenting as a Skin-Colored Dermal Nodule
- Resource Type
- Authors
- Krishna A. J. Mutgi; Mary S. Stone; Pooja Chitgopeker; Heather Ciliberto
- Source
- Pediatric dermatology. 33(1)
- Subject
- medicine.medical_specialty
Pathology
Skin Neoplasms
CD34
Antigens, CD34
Dermatology
Fibroma
Diagnosis, Differential
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Dermatofibrosarcoma protuberans
Medicine
Neoplasm
Humans
Child
Dermal Nodule
integumentary system
business.industry
Dermal Fibroma
medicine.disease
stomatognathic diseases
030220 oncology & carcinogenesis
Pediatrics, Perinatology and Child Health
Female
Differential diagnosis
Dermal dendrocyte hamartoma
business
- Language
- ISSN
- 1525-1470
Plaque-like CD34-positive dermal fibromas, also known as medallion-like dermal dendrocyte hamartomas (MDDHs), are a recently recognized group of congenital and acquired spindle cell neoplasms that may appear histologically similar to dermatofibrosarcoma protuberans. Recognizing the clinical heterogeneity of this neoplasm and the subtle pathologic differences are crucial to making the correct diagnosis and avoiding the aggressive surgical intervention required to treat a dermatofibrosarcoma protuberans. We present the case of a 9-year-old girl with an acquired variant of a plaque-like CD34-positive dermal fibroma without clinical epidermal change. Our case expands the clinical spectrum to include an acquired variant of a plaque-like CD34-positive dermal fibroma without clinical epidermal change. Examination of more cases is needed to determine whether all clinical variants are truly subtypes of the same neoplasm or represent distinct CD34-positive spindle cell proliferations.