Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
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- McGranahan, N, Rosenthal, R, Hiley, CT, Rowan, AJ, Watkins, TBK, Wilson, GA, Birkbak, NJ, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Blackhall, F & Crosbie, P 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell . https://doi.org/10.1016/j.cell.2017.10.001
Cell, vol. 171, no. 6, pp. 1259-1271.e11
McGranahan, N, Rosenthal, R, Hiley, C T, Rowan, A J, Watkins, T B K, Wilson, G A, Birkbak, N J, Veeriah, S, Van Loo, P, Herrero, J, Swanton, C, Jamal-Hanjani, M, Shafi, S, Czyzewska-Khan, J, Johnson, D, Laycock, J, Bosshard-Carter, L, Gorman, P, Hynds, R E, Wilson, G, Horswell, S, Mitter, R, Escudero, M, Stewart, A, Rowan, A, Xu, H, Turajlic, S, Abbosh, C, Goldman, J, Stone, R K, Denner, T, Matthews, N, Elgar, G, Ward, S, Costa, M, Begum, S, Phillimore, B, Chambers, T, Nye, E, Graca, S, Al Bakir, M, Joshi, K, Furness, A, Ben Aissa, A, Wong, Y N S, Georgiou, A, Quezada, S, Hartley, J A, Lowe, H L, Lawrence, D, Hayward, M, Panagiotopoulos, N, Kolvekar, S, Falzon, M, Borg, E, Marafioti, T, Simeon, C, Hector, G, Smith, A, Aranda, M, Novelli, M, Oukrif, D, Janes, S M, Thakrar, R, Forster, M, Ahmad, T, Lee, S M, Papadatos-Pastos, D, Carnell, D, Mendes, R, George, J, Navani, N, Ahmed, A, Taylor, M, Choudhary, J, Summers, Y, Califano, R, Taylor, P, Shah, R, Krysiak, P, Rammohan, K, Fontaine, E, Booton, R, Evison, M, Crosbie, P, Moss, S, Idries, F, Joseph, L, Bishop, P, Chaturved, A, Quinn, A M, Doran, H, Leek, A, Harrison, P, Moore, K, Waddington, R, Novasio, J, Blackhall, F, Rogan, J, Smith, E, Dive, C, Tugwood, J, Brady, G, Rothwell, D G, Chemi, F, Pierce, J, Gulati, S, Naidu, B, Langman, G, Trotter, S, Bellamy, M, Bancroft, H, Kerr, A, Kadiri, S, Webb, J, Middleton, G, Djearaman, M, Fennell, D, Shaw, J A, Le Quesne, J, Moore, D, Nakas, A, Rathinam, S, Monteiro, W, Marshall, H, Nelson, L, Bennett, J, Riley, J, Primrose, L, Martinson, L, Anand, G, Khan, S, Amadi, A, Nicolson, M, Kerr, K, Palmer, S, Remmen, H, Miller, J, Buchan, K, Chetty, M, Gomersall, L, Lester, J, Edwards, A, Morgan, F, Adams, H, Davies, H, Kornaszewska, M, Attanoos, R, Lock, S, Verjee, A, MacKenzie, M, Wilcox, M, Bell, H, Hackshaw, A, Ngai, Y, Smith, S, Gower, N, Ottensmeier, C, Chee, S, Johnson, B, Alzetani, A, Shaw, E, Lim, E, De Sousa, P, Barbosa, M T, Bowman, A, Jordan, S, Rice, A, Raubenheimer, H, Proli, C, Cufari, M E, Ronquillo, J C, Kwayie, A, Bhayani, H, Hamilton, M, Bakar, Y, Mensah, N, Ambrose, L, Devaraj, A, Buderi, S, Finch, J, Azcarate, L, Chavan, H, Green, S, Mashinga, H, Nicholson, A G, Lau, K, Sheaff, M, Schmid, P, Conibear, J, Ezhil, V, Ismail, B, Irvin-sellers, M, Prakash, V, Russell, P, Light, T, Horey, T, Danson, S, Bury, J, Edwards, J, Hill, J, Matthews, S, Kitsanta, Y, Suvarna, K, Fisher, P, Keerio, A D, Shackcloth, M, Gosney, J, Postmus, P, Feeney, S, Asante-Siaw, J, Aerts, H J W L, Dentro, S & Dessimoz, C 2017, ' Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution ', Cell, vol. 171, no. 6, pp. 1259-1271.e11 . https://doi.org/10.1016/j.cell.2017.10.001 - Subject
Male immune-editing 0301 basic medicine DOWN-REGULATION immune-escape Lung Neoplasms Loss of Heterozygosity Cohort Studies Loss of heterozygosity HLA Antigens Carcinoma, Non-Small-Cell Lung Chromosome instability MUTATIONAL PROCESSES 11 Medical and Health Sciences Aged, 80 and over Antigen Presentation cancer evolution Manchester Cancer Research Centre bioinformatics Middle Aged 3. Good health Female loss of heterozygosity SENSITIVITY Life Sciences & Biomedicine Adult Biochemistry & Molecular Biology chromosomal instability Antigen presentation Locus (genetics) NEOANTIGENS Human leukocyte antigen Biology Polymorphism, Single Nucleotide General Biochemistry, Genetics and Molecular Biology 03 medical and health sciences Immune system copy number medicine Humans Lung cancer Aged Science & Technology ResearchInstitutes_Networks_Beacons/mcrc CTLA-4 BLOCKADE Cell Biology 06 Biological Sciences medicine.disease PD-1 BLOCKADE neoantigen lung cancer 030104 developmental biology Carcinoma, Non-Small-Cell Lung/genetics Carcinoma, Non-Small-Cell Lung/immunology Carcinoma, Non-Small-Cell Lung/pathology Carcinoma, Non-Small-Cell Lung/therapy HLA Antigens/genetics HLA Antigens/immunology Lung Neoplasms/genetics Lung Neoplasms/immunology Lung Neoplasms/pathology Lung Neoplasms/therapy Mutation Tumor Escape heterogeneity TRACERx Consortium DISCOVERY CELLS Immunology RESISTANCE Developmental Biology - Language
- English
- ISSN
- 0092-8674