Enhanced Oxygen Singlet Production by Hybrid System of Porphyrin and Enriched (6,5) Single-Walled Carbon Nanotubes for Photodynamic Therapy
- Resource Type
- Authors
- Ynara Marina Idemori; Rafael N. Gontijo; Cristiano Fantini; G. A. M. Sáfar; Klaus Krambrock; Dayse Carvalho da Silva Martins; Maurício V. B. Pinheiro
- Source
- The Journal of Physical Chemistry C. 119:4344-4350
- Subject
- Physics::Biological Physics
Chemistry
medicine.medical_treatment
Absorption cross section
chemistry.chemical_element
Photodynamic therapy
Carbon nanotube
Photochemistry
Porphyrin
Oxygen
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
law.invention
Condensed Matter::Materials Science
chemistry.chemical_compound
General Energy
law
Physics::Atomic and Molecular Clusters
medicine
Singlet state
Physical and Theoretical Chemistry
Absorption (electromagnetic radiation)
Chirality (chemistry)
- Language
- ISSN
- 1932-7455
1932-7447
We demonstrate that hybrid systems of porphyrins and chirality enriched (6,5) single-walled carbon nanotubes (E-SWCNTs) are better candidates for photodynamic therapy (PDT) than their components alone. Surprisingly, the E-SWCNTs act as optical absorption enhancers to the porphyrins increasing the oxygen singlet production when illuminated by a light source with energy higher than the E-SWCNT gap plus the equivalent in energy of an E-SWCNT phonon. The phenomenon is explained based on energy transfer from the E-SWCNT to the porphyrin which finally transfers it to the oxygen molecule. The large optical absorption cross section of E-SWCNT and the resonance of the porphyrin to the oxygen singlet–triplet transition are responsible for the synergistic effect.