Funding Acknowledgements Type of funding sources: None. Introduction The recently proposed classification of the Society of Cardiovascular Angiography and Interventions (SCAI) stratifies cardiogenic shock (CS) in 5 stages from least to greatest severity (1,2). The aim of this project is to apply the SCAI classification to a cohort of patients in CS and analyze the results among the different stages. Methods Retrospective study of CS patients attended by our multidisciplinary team between September 2014-December 2020. The patients were assigned to one of the 5 stages by two independent cardiologists. SCAI subgroups were interpreted considering the recent consensus statement; based on clinical, laboratory, and hemodynamic parameters. In-hospital mortality was the main outcome analyzed. Results 163 patients were included. Mean age was 55 years (44-62), 76% were male. 9 patients (6%) were assigned to SCAI class C, 55 (34%) D and 99 (61%) in E. There was an almost perfect concordance between the two independent cardiologists when performing the classification (kappa =0.93, p In-hospital mortality was 11%, 31%, and 59% in stages C, D, and E respectively (p Conclusion The SCAI classification is easy to apply in clinical practice and provides a firm prediction of the prognosis of patients in CS. Each SCAI class was significantly associated with the primary endpoint. Its widespread use would allow the optimization of communication between professionals, as well as serve as the basis for the design of future research projects.