Level of consciousness and memory during the intracarotid sodium amobarbital procedure
- Resource Type
- Authors
- E. E. Moore; David W. Loring; Ramon Figueroa; M. E. Nichols; Kimford J. Meador; Gregory P. Lee
- Source
- Brain and cognition. 33(2)
- Subject
- Adult
Male
medicine.medical_specialty
Neurology
Adolescent
Consciousness
Cognitive Neuroscience
Amobarbital
media_common.quotation_subject
Experimental and Cognitive Psychology
Lateralization of brain function
Level of consciousness
Arts and Humanities (miscellaneous)
Memory
Aphasia
Developmental and Educational Psychology
medicine
Humans
Hypnotics and Sedatives
Glasgow Coma Scale
Dominance, Cerebral
media_common
Coma
Analysis of Variance
Middle Aged
Neuropsychology and Physiological Psychology
Cross-Sectional Studies
Epilepsy, Temporal Lobe
Anesthesia
Female
medicine.symptom
Psychology
Neuroscience
medicine.drug
- Language
- ISSN
- 0278-2626
Controversy exists regarding differential effects on consciousness of left/right cerebral inactivation via intracarotid amobarbital. Further, the effects of level of consciousness (LOC) on memory during the intracarotid sodium amobarbital procedure (IAP) are unclear. A modified version of the Glasgow Coma Scale altered to avoid the confounding effects of aphasia was employed to assess LOC in 97 patients during the IAP. A greater impairment in LOC occurred with left cerebral inactivation. Memory was more impaired following left hemisphere injections as well as from injections contralateral to seizure focus. Memory was correlated with LOC, and this effect was more prominent for right hemisphere injections and for injections ipsilateral to seizure focus. These findings support differential cerebral roles in consciousness and demonstrate that IAP memory performance may be affected by the patient's LOC.