Background: Post-COVID-19 syndrome has been found in patients admitted to a hospital with severe conditions of COVID-19 and in adults who initially presented a mild illness. The aim is to underline the available literature on post-COVID-19 follow-up until 12 months about symptoms reported by adults infected with Sars-Cov-2 from at least 12 weeks after disease onset. Methods: The bibliographic search was conducted on PubMed, Embase, CINHAL, Scopus and the Cochrane Central Register of Controlled Studies. Results: We found that 68% of patients had at least one symptom post-COVID-19 after 12 weeks and up to 24 weeks post-onset. The most frequent symptoms were fatigue and muscle weakness (26%), dizziness and mental clouding (15%) and taste disturbances (10%). Conclusions: Health policy needs to prepare for a long-term management plan to address COVID-19, as there are significant needs beyond recovery from the acute infection.