The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures
- Resource Type
- Authors
- Sgueglia, G; Longobardi, S; Valerio, D; Campitiello, Mr; Colacurci, N; Di Pietro, C; Battaglia, R; D'Hooghe, T; Altucci, L; Dell'Aversana, C
- Source
- Subject
- Fertility
IVF
Reproduction
Genetics
Epigenetics, Fertility, IVF, Reproduction
Epigenetics
Molecular Biology
Genetics (clinical)
Developmental Biology
- Language
The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main epigenetic modifications that may influence female reproduction and could affect IVF success. Graphical Abstract