The examination of a decomposed cadaver is inherently difficult with varying degrees of decomposition encountered and the possibility of predation related damage then masking or hampering assessment of injuries and underlying pathology. These cases should be approached with caution and require a full autopsy examination to obtain the maximum amount of information, be that positive findings or the absence of significant injuries. It is advised that if at any point during the post-mortem examination concerning findings are encountered then the examination should be stopped with further information, clarification or advice sought. Despite the presence of putrefactive change and tissue autolysis, additional investigations are potentially useful with histology and toxicology considered important in such cases to reach a conclusion in the cause of death, be that unascertained.