Amine-Controlled Reduction of 2-Aminochromone-3-Carbaldehyde with Zn and Acetic Acid
- Resource Type
- Authors
- Tapas Sarkar; Jaydip Ghosh; Pritam Biswas; Chandrakanta Bandyopadhyay
- Source
- Journal of Chemical Research. 39:734-737
- Subject
- Reduction (complexity)
Acetic acid
chemistry.chemical_compound
chemistry
chemistry.chemical_element
Amine gas treating
General Chemistry
Clemmensen reduction
Zinc
Nuclear chemistry
- Language
- ISSN
- 2047-6507
1747-5198
On heating with zinc in acetic acid 2-(N-arylamino)chromone-3-carbaldehydes produce 2-(N-arylamino)-3-methylchromones, whereas 2-(N-alkylamino)chromone-3-carbaldehydes produce 4-hydroxy-3-methylcoumarin in moderate yields. Reduction of an aldehyde function to a methyl group has been achieved under very mild reaction conditions.