Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 Patients
- Resource Type
- Authors
- Mehmet Yildirim; Burcin Halacli; Deniz Yuce; Yunus Gunegul; Ebru Ortac Ersoy; Arzu Topeli
- Source
- Journal of Intensive Care Medicine. 38:70-77
- Subject
- Hospitalization
Intensive Care Units
SARS-CoV-2
Critical Illness
Humans
COVID-19
Critical Care and Intensive Care Medicine
Aged
Retrospective Studies
- Language
- ISSN
- 1525-1489
0885-0666
Purpose We aimed to evaluate the relation between admission COVID-19 associated hyperinflammatory syndrome (cHIS) score and intensive care unit (ICU) outcomes. Materials and Methods Patients with laboratory confirmed COVID-19 admitted to our ICU between 20th March 2020-15th June 2021 were included. Patients who received immunomodulatory treatment except corticosteroids were excluded. Main outcomes were ICU mortality and invasive mechanical ventilation (IMV) requirement after ICU admission. Results Three hundred and seventy patients with a median (IQR) age of 66 (56-77) were analyzed. Median admission cHIS score was 3 (2-4). A cHIS score ≥3 was found to be associated with ICU mortality (sensitivity = 0.63, specificity = 0.50; p 2/FiO2 ratio than others (n = 171) (p Conclusion Critically-ill COVID-19 patients with admission cHIS score ≥3 have worse disease severity and outcomes than other patients.