Additional file 2: Table S1. Diagnostic and therapeutic (ICD-9-CM and ATC) codes used in the current study for drawing records and fields from Healthcare Utilization databases. Lombardy, Italy, 2020–2021. Table S2. Use of specific healthcare services during the 6 months after the matching date (follow-up period), during the corresponding 6 months of the prior year (baseline period) and during the 6 months preceding the matching date (wash-out period) among subjects who did not use Dupilumab and were 1:1 matched to those who used it.