Cervical metastases from maxillary squamous cell carcinoma: retrospective analysis and review of the literature
- Resource Type
- Authors
- Ayesha Dalal; Andrew McLennan
- Source
- British Journal of Oral and Maxillofacial Surgery. 51:702-706
- Subject
- Adult
Male
Palate, Hard
medicine.medical_specialty
medicine.medical_treatment
Disease-Free Survival
Metastasis
Alveolar Process
medicine
Retrospective analysis
Humans
Neoplasm Invasiveness
Basal cell
Aged
Neoplasm Staging
Retrospective Studies
Aged, 80 and over
Maxillary Neoplasms
Salvage Therapy
Gingival Neoplasms
Palatal Neoplasms
business.industry
Alveolar process
Primary resection
Incidence (epidemiology)
Neck dissection
Middle Aged
Plastic Surgery Procedures
respiratory system
medicine.disease
Surgery
Survival Rate
stomatognathic diseases
Treatment Outcome
medicine.anatomical_structure
Otorhinolaryngology
Lymphatic Metastasis
Carcinoma, Squamous Cell
Neck Dissection
Female
Radiotherapy, Adjuvant
Hard palate
Neoplasm Recurrence, Local
Oral Surgery
business
Follow-Up Studies
- Language
- ISSN
- 0266-4356
The purpose of this study was to define the incidence of cervical metastasis in squamous cell carcinoma (SCC) of the maxillary alveolus, hard palate and gingiva; to identify patterns of locoregional failure and to assess survival outcomes. We retrospectively analysed 30 patients treated for SCC of the maxillary alveolus and hard palate between 2000 and 2010. Parameters assessed included the incidence of cervical metastasis at presentation and recurrence, paying particular attention to tumour staging and survival outcomes. Of our 30 patients, 25 were confirmed to have T4 SCC of the maxillary alveolus and hard palate with bone invasion. Cervical metastases had been noted in 7 (23%) patients at initial presentation. A total of 9 (36%) patients developed regional failure in the pT4 SCC group shortly after primary resection. Patients with advanced primary SCC of the hard palate and maxillary alveolus (particularly when there was bone invasion) showed high rates of regional failure, and in most cases successful salvage was not achieved. Based on our findings and a review of the existing literature we strongly recommend elective neck dissection for patients with pT4 SCC of the maxillary alveolus and hard palate.