Positive bladder cooling reflex in patients with bladder outlet obstruction due to benign prostatic hyperplasia
- Resource Type
- Authors
- Yoko Yoshikawa; Atsuo Kondo; Atsuya S. Kondo; Shinichi Ohshima; Momokazu Gotoh; Yoshinari Ono
- Source
- World journal of urology. 17(2)
- Subject
- Nephrology
Male
medicine.medical_specialty
Urology
medicine.medical_treatment
Prostatic Hyperplasia
urologic and male genital diseases
Bladder outlet obstruction
Prostate
Internal medicine
Reflex
Medicine
Humans
In patient
Saline
Aged
Aged, 80 and over
Urinary bladder
business.industry
respiratory system
Hyperplasia
Middle Aged
medicine.disease
female genital diseases and pregnancy complications
Cold Temperature
Urinary Bladder Neck Obstruction
medicine.anatomical_structure
business
circulatory and respiratory physiology
- Language
- ISSN
- 0724-4983
The bladder cooling reflex was evaluated in patients with bladder outlet obstruction to study the effect of obstruction on the afferent neural function of the bladder, especially on the C-afferents. The bladder cooling test was performed by infusion of 0 degree C saline into the bladder with simultaneous detrusor pressure measurement in 104 patients with bladder outlet obstruction due to benign prostatic hyperplasia. In 49 patients (47%) a positive cooling reflex was observed. This was defined as a rise in the detrusor pressure following cold saline instillation exceeding 15 cmH2O (range 15-130 cmH2O, mean 60.6 cmH2O; positive group). In the remainder of cases the pressure rise ranged from 0 to 12 cmH2O (mean 6.1 cmH2O; negative group). Bladder outlet obstruction may cause some alteration in the afferent neural function of the bladder, in particular of the C-afferent fibers.