An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation
- Resource Type
- Authors
- Karanasiou, G. S.; Tsompou, P. I.; Tachos, N.; Karanasiou, G. E.; Sakellarios, A.; Kyriakidis, S.; Antonini, L.; Pennati, G.; Petrini, L.; Gijsen, F.; Nezami, F. R.; Tzafriri, R.; Fawdry, M.; Fotiadis, D. I.
- Source
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2021
- Subject
- Clinical Trials as Topic
Time Factors
Angioplasty
Absorbable Implants
Coronary
Humans
Drug-Eluting Stents
Angioplasty, Balloon, Coronary
Balloon
- Language
- ISSN
- 2694-0604
The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.