Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019
- Resource Type
- Authors
- Kimberly C. Claeys; Surbhi Leekha; Hyunuk Seung; Anthony Amoroso; Megan Tripoli; Jacqueline T. Bork; Emily L. Heil
- Source
- Infection Control and Hospital Epidemiology
Infection Control & Hospital Epidemiology
- Subject
- 0301 basic medicine
Microbiology (medical)
medicine.medical_specialty
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Epidemiology
030106 microbiology
03 medical and health sciences
0302 clinical medicine
Drug Resistance, Multiple, Bacterial
Internal medicine
Gram-Negative Bacteria
medicine
Humans
030212 general & internal medicine
Antibiotic use
Gram
SARS-CoV-2
business.industry
Concise Communication
COVID-19
Interrupted time series
medicine.disease
Hospitals
Calendar period
Anti-Bacterial Agents
Multiple drug resistance
Pneumonia
Infectious Diseases
Gram-Negative Bacterial Infections
business
- Language
- ISSN
- 1559-6834
0899-823X
Interrupted time series segmented regression was conducted to trend antibiotic use and multidrug-resistant gram-negative (MDRGN) acquisition relative to COVID-19 in an academic hospital. Total antibiotic use and antibiotic use related to pneumonia was higher in the period after the onset of COVID-19 compared to the similar calendar period in 2019. Furthermore, MDRGN acquisition increased 3% for every increase in positive COVID-19 tests per week.