Prediction of peri-operative adverse respiratory events in children: the role of exhaled nitric oxide
- Resource Type
- Authors
- B. S. von Ungern-Sternberg; Anoop Ramgolam; Graham L. Hall; Guicheng Zhang; Mary Hegarty
- Source
- Anaesthesia. 70:1160-1164
- Subject
- Male
medicine.medical_specialty
Pediatrics
Adolescent
Predictive capability
Anesthesia, General
Nitric Oxide
Postoperative Complications
Predictive Value of Tests
Internal medicine
Wheeze
Preoperative Care
Humans
Medicine
Routine clinical practice
Respiratory system
Child
business.industry
Perioperative
Respiration Disorders
Anesthesiology and Pain Medicine
Breath Tests
Case-Control Studies
Child, Preschool
Exhaled nitric oxide
Female
Minor Surgical Procedures
medicine.symptom
business
Biomarkers
- Language
- ISSN
- 0003-2409
Summary Increased levels of exhaled nitric oxide (eNO) may be a more objective predictor in identifying children at higher risk of peri-operative adverse respiratory events than the presence of risk factors such as recent cold or wheeze. Children with either none or ≥ 2 risk factors had eNO measured before surgery and any peri-operative adverse respiratory events were recorded. We found that an elevated eNO level was only predictive of adverse respiratory events in children with ≥ 2 risk factors (OR 2.96 (95% CI 1.48–5.93), p = 0.002). The presence of risk factors had a better predictive capability than a raised eNO level (OR 3.83 (95% CI 1.85–7.95), p