Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency
- Resource Type
- Authors
- Curtis D Froehlich; Shelley Hancock; Veronica Armijo-Garcia; Andrew D. Meyer
- Source
- Perfusion
- Subject
- Male
medicine.medical_specialty
Ellis-Van Creveld Syndrome
Oxygenation index
medicine.medical_treatment
Article
Extracorporeal
Pulmonary function testing
03 medical and health sciences
Extracorporeal Membrane Oxygenation
0302 clinical medicine
medicine
Extracorporeal membrane oxygenation
Humans
Jeune syndrome
Radiology, Nuclear Medicine and imaging
Registries
Advanced and Specialized Nursing
030222 orthopedics
business.industry
General Medicine
Surgery
Respiratory failure
Cardiothoracic surgery
Child, Preschool
Life support
Respiratory Insufficiency
Cardiology and Cardiovascular Medicine
business
Safety Research
030217 neurology & neurosurgery
- Language
- ISSN
- 1477-111X
0267-6591
Introduction:Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry.Case Report:A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support.Discussion:The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO.Conclusion:ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.