SECEDO: SNV-based subclone detection using ultra-low coverage single-cell DNA sequencing
- Resource Type
- Authors
- Hana Rozhoňová; Daniel Danciu; Stefan Stark; Gunnar Rätsch; André Kahles; Kjong-Van Lehmann
- Source
- Bioinformatics, 38 (18)
- Subject
- Statistics and Probability
Genome
Base Sequence
High-Throughput Nucleotide Sequencing
Bayes Theorem
Sequence Analysis, DNA
Polymorphism, Single Nucleotide
Biochemistry
Computer Science Applications
Computational Mathematics
Computational Theory and Mathematics
Neoplasms
Humans
Molecular Biology
- Language
- ISSN
- 1367-4811
1367-4803
1460-2059
Motivation Several recently developed single-cell DNA sequencing technologies enable whole-genome sequencing of thousands of cells. However, the ultra-low coverage of the sequenced data (
Bioinformatics, 38 (18)
ISSN:1367-4803
ISSN:1460-2059