The ABO and Rh blood group are the most important systems with various distributions reported for different populations. The ABO and Rh are known also to be associated with various diseases. Obesity is a complex chronic disease involving environmental, genetics, physiologic, metabolic, behavioral, and psychological components. The present study is aimed to explore the association and distribution of the ABO/Rh blood type and the risk of hypertension and obesity among students population. The study group consisted of 100 examinees, 14 males and 86 females, students aged 18 - 23. The blood group A was found to be the most prevalent (46 %), while the blood group AB was found to be the least prevalent (6%). The highest average value of the BMI was found in subjects with the blood group AB/Rh+ 22.36 ± 2.49 kg/m2 where the lowest value was in the blood group B/Rh+ 20.13 ± 2.64 kg/m2. The highest average value of systolic blood pressure was measured in subjects with A/Rh- 138.88 ± 16.63 mm Hg, while the lowest was in the blood group B/Rh- 118.50 ±7.55 mm Hg.