Past research has shown that general and intrinsic religiosity is related to higher Big Five Agreeableness, Conscientiousness and, to some extent, Extraversion. With the rise of the six-factor HEXACO (Honesty–Humility, Emotionality, eXtraversion, Agreeableness, Conscientiousness, Openness) model of personality, however, a more differentiated look at religiousness and personality is called for. It has been suggested that religiosity is more associated with Honesty–Humility than with Agreeableness. The new personality factor, Honesty–Humility has also been shown to have null or weak relations with happiness. In 5 studies involving 1375 participants from Iran, Poland, and Malaysia, the relations of Honesty–Humility and other HEXACO dimensions to religious orientation and well-being outcomes were investigated. As expected, Honesty–Humility was one of the strongest personality correlate of religiosity. Higher scores on religiousness were also associated with Agreeableness, Conscientiousness, and to some extent, Extraversion showing that the main personality characteristics of religiosity are consistent across religious contexts and personality models. Relations of Honesty–Humility to psychological well-being scales were consistently positive and stronger than its relations to subjective well-being measures, suggesting that Honesty–Humility may not be “bad” for pleasure attainment and pain avoidance, but it is definitely “good” for living a virtuous, fully functioning life.