Comparison of the Performances of Two In-House Rapid Methods for Antitubercular Drug Susceptibility Testing ▿
- Resource Type
- Authors
- Emma J. Stella; Héctor R. Morbidoni; Agustina I. de la Iglesia
- Source
- Subject
- Tuberculosis
medicine.drug_class
Antibiotics
Antitubercular Agents
Drug resistance
Microbial Sensitivity Tests
Microbiology
Mycobacterium tuberculosis
medicine
Pharmacology (medical)
Antibacterial agent
Pharmacology
Analytical Procedures
biology
business.industry
Isoniazid
Reproducibility of Results
Mycobacteriophages
Reference Standards
biology.organism_classification
medicine.disease
Infectious Diseases
Streptomycin
Colorimetry
business
Rifampicin
medicine.drug
- Language
- English
Resistance to rifampin (rifampicin), isoniazid, and streptomycin of 69 Mycobacterium tuberculosis isolates was analyzed by an in-house method based on mycobacteriophage D29 and a colorimetric micromethod. Both methods showed sensitivity and specificity values ranging from 93% to 100%. These simple methods offer an option for drug resistance assessment of M. tuberculosis .