Drab Marcin, Szymczyk Agnieszka, Tomczak Waldemar, Drab-Urbanek Elżbieta, Łapacz Katarzyna, Hus Marek, PodhoreckaMonika. Chest pain in the course of multiple myeloma - a clinical case study. Journal of Education, Health and Sport. 2018;8(7):11-18. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1256175 http://ojs.ukw.edu.pl/index.php/johs/article/view/5537 https://pbn.nauka.gov.pl/sedno-webapp/works/866365 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.05.2018. Revised: 18.05.2018. Accepted: 30.05.2018. Chest pain in the course of multiple myeloma - a clinical case study Marcin Drab1, Agnieszka Szymczyk2,3, Waldemar Tomczak2, ElżbietaDrab‑Urbanek3, Katarzyna Łapacz1, Marek Hus3, MonikaPodhorecka3 1 Studenckie Koło Naukowe Przy Klinice Hematoonkologii i Transplantacji Szpiku, Uniwersytet Medyczny w Lublinie 2 Samodzielna Pracownia Transplantologii Klinicznej, Uniwersytet Medyczny w Lublinie 3 Klinika Hematoonkologii i Transplantacji Szpiku, Uniwersytet Medyczny w Lublinie *Autor Korespondencyjny: Agnieszka Szymczyk Samodzielna Pracownia Transplantologii Klinicznej Uniwersytetu Medycznego w Lublinie ul. Staszica 11, 20-081 Lublin Tel: (+48-81) 534 54 48 E-mail: agnieszka.szymczyk.med@wp.pl Key words: multiple myeloma, chest pain, cancer pain Abstract: Introduction: Multiple myeloma (MM) is a rare blood cell proliferative disease characterized by the accumulation and proliferation of monoclonal plasmocytes. Clinical picture of MM includes bone pain, underlying osteolytic lesions, osteopenia or osteoporosis that often lead to pathological fractures. Aim: To draw attention to the unusual cause of chest pain and the holistic approach to analgesic therapy in patients with MM. Case report: A clinical case of a 66-year-old patient with chest pain intensified when moving and deep breathing was presented and cardiological and gastroenterological reasons were excluded. Initially, non-steroidal analgesics and weak opioids were used in the treatment with good effect, however, as time was passing the pain symptoms progressed. Diagnostic imaging was complemented by computed tomography which revealed massive destructive changes within the ribs with the presence of soft tissue masses infiltrating adjacent muscles. Based on additional tests, the patient was diagnosed with MM. Optimization of analgesic therapy has brought permanent pain relief and improved his quality of life. Summary: The modern approach to anelgesia in patients with MM includes not only the use of analgesics, but also radiotherapy, bisphosphonates/zoledronic acid, orthopaedic treatment and chemotherapy.