Chromosome 3p12.3-p14.2 and 3q26.2-q26.32 Are Genomic Markers for Prognosis of Advanced Nasopharyngeal Carcinoma.
- Resource Type
- Article
- Authors
- Sheu, Jim Jinn-Chyuan; Lee, Chia-Huei; Ko, Jenq-Yuh; Tsao, George S. W.; Wu, Chung-Chun; Fang, Chih-Yeu; Tsai, Fuu-Jen; Hua, Chun-Hung; Chen, Chi-Long; Chen, Jen-Yang
- Source
- Cancer Epidemiology, Biomarkers & Prevention; Oct2009, Vol. 18 Issue 10, p2709-2716, 8p, 5 Graphs
- Subject
- Language
- ISSN
- 10559965
The article presents a study which aims to identify susceptible gene loci in advanced nasopharyngeal carcinoma. The study used a genome-wide survey of gene copy number changes and expression levels in the genomes of nasopharyngeal carcinoma cell lines by array-based comparative genomic hybridization analysis. It reveals that there is altered expression of genes which can be associated with malignant progression and can be potential markers for nasopharyngeal carcinoma.